>>692>>685>cnt'dAfter two weeks of using oxiracetam on and off, I'm going to have to take a break. When I'm not using racetams, I perform just as well as when I'm not taking them; there was an increase in mental performance when I started taking them, but now my brain operates that way normally. Now, when I take oxiracetam, my brain becomes overstimulated and I get many of the effects of excess acetylcholinergic activity - stiff neck & jaw, hypertension all over, anxiety, difficulty breathing, etc. Not pleasant, and too distracting to perform well.
I also found that taking caffeine in doses greater than 100mg drastically increased the chance of becoming overstimulated, and the severity of those symptoms.
I'm going to take a week's break, and if I see a decline after that will fall back to piracetam.
I've also found that I no longer need to take supplemental choline, as I the eggs I eat daily provide enough, and the body recycles acetylcholine. Too much choline has increased the chance of the aforementioned symptoms before.
Finally, I would occasionally get mild symptoms of excitotoxicity (eye and muscle twitches, mild anxiety, headaches) when using oxiracetam. These were mitigated by cutting back heavily on the amount of MSG in my diet.
While racetams seem to have similar effects, they tend to have different effects on different brains. Your mileage may vary and I'd love to hear comparisons from other people.