drg - drugs 2.0

Obligatory gwern link: http://www.gwern.net/Nootropics

>>1902
There's an old noots thread here >>54 from the beginning of drugs 2.0, but I guess it's a bit stale.

Concerta (basically long-term release Ritalin) works very well for me; aside from fixing my dopamine problems it seems to keep me awake and in action.

For the more experimental stuff, starting with piracetam + choline source is good. Don't overdo it (look up isochroma + longecity + piracetam), but unless you eat it like candy you'll be fine. 1-2g twice a day seemed to improve my mood and focus; >5g made me feel on edge, and if I had too many stims, overstimulated.

I also encourage n-backing, which is something I've been meaning to start myself.



I've been trying sunifiram, which is a powerful ampakine (about 1000 times more potent than piracetam). So far, it seems to act like a stimulant (euphoria, mania, and focus), the effects of which last several hours. I then get a small crash. I also tried dosing twice in the same day; that made me crash even harder.

I can't tell whether it is addictive or not; I get withdrawals if I take it daily then stop, but I don't have a psychological addiction to it. I also can't tell whether the long-term potentiation is doing anything good for my memory, which is why I've been meaning to start N-backing.

I can't recommend it as a nootropic, since side effects it has given me are withdrawal, significant muscle twitching, mood switching, and lethargy (with the withdrawal). I've heard unifiram and Noopept are cleaner noots.

>>1907
Forgot to mention, the max dose of sunifiram I'm taking is ~15mg. I have to make a generous estimate with the measuring scoop I have, since I don't have my milligram scale with me.

Anyone here ever used nootropics for depersonalization and anxiety? Last year I entered a really heavy state of depersonalization exacerbated by daily marijuana use all day. I've since quit smoking weed and started exercising, and take entry-level noots since I never have the money/patience to buy online and the only soykaf in my town is stuff like Vinpocetine and Theanine and Choline and Fish Oil. While those are good and have helped me get over like 95 percent of the depersonalization/derealization there's still a bit there and I still get really anxious racing thoughts sometimes. Are there any specific noots that can help kill that last 5 percent of this or am I stuck with it forever?

>>1947
I know that piracetam helped reverse my dissociation from DXM use. Dissociation and depersonalization are different things though.

>>1948
Yeah but they're fairly similar. I'll try to acquire some capital and grab some off line

>>1949
Honestly, m8, piracetam's legal, and easy and cheap to buy online, and it ships quickly. Unless you have a local source I recommend buying it online. /r/nootropics has plenty of vendors.

>That being said, what she wants out of the situation is to be able to work full time then come home and study programming without feeling absolutely mentally drained.

Just take a nap. It really works wonders.

>>1902
Get alpha-gpc, much higher bioavailability.

The only noots that don't seem like bull soykaf to me are piracetam+alpha-gpc. I feel like the other racetams are just riding the piracetam wave, and everything else is bull.

I'm trying out nsi-189 though, let's see if I can become limitless.

My shrink recently recommended me to take citicoline, has anyone had any experience with it before?

>>1965
Any word on that NSI-189?

>>1988
I noticed some antidepressant effects but nothing noticeable cognitively. I admittedly fuarrrked up the trials by smoking weed/taking 2cb though but it seemed pretty good. Have been taking 40~mg a day in bombs.